Programme

Wednesday, September 30th 2026

Until 11:30 am: Check-In at Hotel Holiday Inn Express Wuppertal, Wall 39, 42103 Wuppertal

11:30 Transfer from hotel to Bayer AG Elberfeld site via historic Schwebebahn

12:00 Registration

12:30  Lunch/Get-together

13:30 Welcome

Session 1 (Chair Claudia Jessen-Trefzer)

13:35 Luca Denkler, Bunescu Lab (T1)

Iron photocatalysis for sustainable carboxylic acid valorization

13:55 Jörg Gries, Bayer AG

A high Dose of Complexity – Chemical Development of an Anticancer Drug

14:15 Coffee Break

14:30 Site Visit (#1) and Site Visit (#2)

Session 2 (Chair John J. Molloy)

16:00 Lenard Saile, Pappas Lab (T2)

Chirality makes or breaks chemically driven self-assembly

16:20 Carina Dettenrieder & Scherin Fajad, Bachem AG

From bench to patients: an integrated CMC development path for scalable peptide manufacturing

16:40 Group Picture

17:00 Coffee Break

Session 3 (Chair Jola Pospech)

17:15 Mariia Zmyslia, Jessen-Trefzer Lab (T4)

Programmable Encapsulins for Biomedical Applications

17:35 Jan Schütz, DSM-Firmenich

Catalytic routes to vitamin A acetate

17:55 Jörg Dietzel, Walker Lab (T5)

Diastereoselective synthesis of 5-azabicyclo[2.1.1]hexanes

18:15 Walk from site to hotel

19:00 Dinner

Thursday, October 1st 2026

8:00 8:15 Transfer from hotel Bayer AG R&D site in Aprath

Session 4 (Chair Sebastian B. Beil)

9:00 Jonas Klagge, Molloy Lab (T6)

Light-enabled access to non-symmetrical α-diboryl radicals leveraging multifunctional C1 building blocks

9:20 Maximilian Koy, Nuvisan

Direct-to-biology for accelerated drug discovery

9:40 Gregor Cresmosnik, Novartis

Discovery of selective low molecular weight interleukin-36 receptor antagonists by encoded library technologies

10:00 Coffee Break

Session 5 (Chair Mario P. Wiesenfeldt)

10:30 Gianna Pölderl, Næsborg Lab (T8)

Long-lived room temperature phosphorescence in aqueous micellar systems: application in cyclobutane synthesis

10:50 Eduardo de Pedro Beato, Sanofi-Aventis

High-throughput condition screening & experimentation in medicinal chemistry

11:10 Dang H. Vu, Wiesenfeldt Lab (T9)

Rapid synthesis of quinolizidines

11:30 Lunch

Session 6 (Chair Lena Barra)

12:45 Berjan Stouwie, Beil Lab (T10)

Nickel-photocatalytic deoxygenative arylation toward β-methyl-branched α-amino acids

13:05 Viktor Vintonyak, Boehringer Ingelheim Pharma GmbH & Co. KG

Discovery of verducatib (BI 1291583): A DPP1 inhibitor clinical candidate for the treatment of bronchiectasis

13:25 Coffee Break

Session 7 (Chair Johannes Walker)

14:15 Debapratim Nag, Galstyan Lab (T11)

Controlling light-driven antimicrobial activity by polymer design in zinc(ii) phthalocyanine-loaded polymeric micelles

14:35 Thomas Schaub, BASF SE

Large scale homogeneous catalysis @ BASF

14:55 Coffee Break

15:30 Anastasia Hager, Bayer AG (Impulse Lecture)

Drug Discovery: Matching target biology with the right modality – Why strategy and focus matter

16:30 Poster Session with beer and Pretzels

18:00 Karl Gademann, Zurich University, Switzerland

Discoveries and Surprises with Natural Products

19:00 Short Break

19:30 Dinner on site

21:30 Transfer to hotel

Friday, October 2nd 2026

8:30 Transfer from hotel to Bayer AG Elberfeld site via historic Schwebebahn

Please be on time and check out of the hotel room before leaving.

Luggage can be stored in designated rooms at the hotels.

Session 8 (Chair Ala Bunescu)

9:00 Lena Barra, Barra Lab

Natural and engineered methyltransferases for biocatalytic terpene precursor modifications

9:20 Ernesto Santandrea, Roche

Development of the commercial manufacturing process of the antibiotic zosurabalpin

9:40 Bianca C. Baciu, Broichhagen Lab (T12)

Design of a new class of cyanine dyes for cellular imaging by dSTORM microscopy

10:00 Coffee Break

Session 9 (Chair Anzhela Galstyan)

10:20 Timo Heinrich, Merck KGaA

Studies on inhibitors of the four TEAD transcription factors with different focus

10:40 Sandra Panczyk, Helfrich Lab (T13)

TailEnzA: Tailoring enzyme-guided expansion of natural product biosynthetic space

11:00 Coffee Break

11:10 Sandra González Gallardo, Wiley-VCH GmbH

Current trends and challenges in scientific publishing

11:30 Poster Prize HTI 2026

11:45 HTI 2026 Announcement and Closing Remarks

12:00 Lunch to Go

12:10 Walk from site to hotel